British Dragon Clomiphene Tablets 100 tabs (50 mg/tab)

Clomiphene Citrate – Clomid

Clomiphene Citrate (commonly known as Clomid) is a synthetic non-steroidal medication closely resembling estrogen. This drug is primarily utilized as an ovulatory stimulant due to its ability to bind with estrogen receptors in the hypothalamus, effectively blocking the detection of natural estrogen. Consequently, the hypothalamus stimulates the pituitary gland to release increased levels of gonadotropins, such as FSH and LH, which subsequently promotes ovarian or testicular production of estrogen or testosterone.

This unique property of Clomid is pivotal in treating women experiencing ovarian failure and those aiming to induce ovulation. Nonetheless, prolonged usage may heighten the risk of ovarian cancer, necessitating careful consideration.

Pharmacology

Indicated for cases of ovulatory dysfunction, Clomid is often prescribed for women struggling to conceive due to ovulation irregularities. Conditions like polycystic ovarian syndrome and other causes of amenorrhea are common underlying issues. A thorough evaluation of the menstrual cycle is crucial before initiating Clomid therapy, which is typically started around the 5th day of the cycle and can span 3-6 cycles. Monitoring body temperature and blood tests is essential to ensure successful ovulation.

Mode of Action

Clomid is a powerful medication. When prescribed correctly for limited durations, it can assist women facing infertility challenges. By mimicking estrogen, Clomiphene binds to hypothalamic receptors, tricking the brain into perceiving low estrogen levels. This, in turn, triggers increased production of gonadotropins, stimulating the ovaries to enhance estrogen synthesis—an important factor for successful fertilization.

Indications

Clomiphene is designated for women experiencing ovulatory dysfunction under specific conditions:

• the female is not pregnant
• no ovarian cysts present (ultrasound required)
• absence of abnormal vaginal bleeding, indicating a thorough cancer evaluation
• normal liver function tests
• though Clomid has seen some success in treating male infertility, its study is limited. It may increase sperm count by promoting LH and FSH surges but bears caution regarding long-term risks, including potential testicular tumors.
• appropriate prescription dosage for infertility

Clomiphene is a large molecule soluble in organic solvents, with the sodium salt citrate being water-soluble. Patients should undergo comprehensive evaluations for gynecological and endocrine disorders prior to Clomid treatment. Ovulation typically occurs within 5-10 days post-initiation, necessitating timely intercourse.

Initial dosing begins at 50 mg/day for 5 days, with potential increases for those not achieving ovulation.

Body Building

Clomid is frequently misused among both amateur and professional athletes alongside various substances such as anabolic steroids and HCG. Unlike typical anabolic steroids, which suppress testosterone, Clomid enhances testosterone levels by stimulating LH release.

Many anabolic steroids possess androgenic properties and may convert into estrogen in fatty tissues, leading to gynecomastia. As a countermeasure, athletes use Clomid to prevent breast enlargement by blocking estrogen receptors. Additionally, its action in the brain prompts LH and FSH release that further stimulates testosterone production, enhancing performance. Bodybuilders may use Clomid alone or in conjunction with other steroids or growth hormones.

Clomid Dosage for Athletes

Clomid is administered daily, often in conjunction with low-potency steroids. Bodybuilders typically cycle anabolic steroid use before transitioning to Clomid for its testosterone-boosting effects while avoiding gynecomastia. Optimal initiation timing is unclear but should occur within 7-10 days post-steroid cessation. Dosage varies, commonly ranging from 50-100 mg/day for two weeks, with some advising dose adjustments based on observed effects. After three weeks, Clomid use should be stopped. Due to its lack of endorsement in bodybuilding, obtaining professional guidance can prove challenging.

Side Effects

When taken at recommended doses for short periods, Clomid is generally deemed safe. Most adverse reactions are temporary and resolve post-treatment.

Common side effects may include:

• flushing
• abdominal discomfort
• nausea and vomiting
• breast tenderness
• headaches
• abnormal vaginal bleeding
• general fatigue
• hair loss
• visual disturbances

Notably, prolonged use can lead to serious visual changes due to potential pituitary gland swelling affecting visual nerve function. Immediate cessation of Clomid is advised upon experiencing any vision alterations, with an ophthalmologist consult recommended.

Mood Changes

Clomid can also cause mood alterations like depression, anxiety, and aggression. While these effects are concerning, clinical trial data indicates they occur in less than 1% of women. Information on bodybuilders experiencing these issues remains sparse.

Cost

A prescription is necessary for Clomid in infertility treatment; however, it is widely accessible online without one. Prices for clomiphene typically range from $50-100 for 100 tablets (25-50 mg each).

Levels

Clomiphene remains easily accessible, but its usage is banned in professional sports. Urinary detection occurs for 5-12 days post-use, with advanced testing protocols in place to monitor the testosterone to estrogen ratios, suggesting potential abuse of the substance.