Euro-Pharmacies Cialis 50 tabs (20 mg/tab)

Tadalafil – Cialis

Tadalafil is a potent medication classified as a phosphodiesterase type 5 (PDE5) inhibitor. Commonly marketed under the brand name Cialis for treating erectile dysfunction and Adcirca for pulmonary arterial hypertension, this medication offers effective solutions for both conditions.

Characteristics of Tadalafil include:

Mechanism of Action

• Tadalafil inhibits the enzyme phosphodiesterase type 5 (PDE5), preventing the breakdown of cyclic guanosine monophosphate (cGMP).
• It enhances blood flow during sexual arousal by increasing cGMP levels through the release of nitric oxide (NO).
• This mechanism results in the relaxation of smooth muscles in blood vessels, facilitating an erection.

Indications

• Used to effectively manage erectile dysfunction in men.
• Also indicated for benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension as Adcirca.

Onset of Action

• Typically, Tadalafil begins to work within 30 minutes to 1 hour post-administration.

Duration of Action

• The efficacy of Tadalafil extends for up to 36 hours, earning it the nickname “weekend pill.”
• This duration allows for flexibility in achieving an erection when sexually stimulated.

Dosage

• For erectile dysfunction, a usual dose of 10 mg or 20 mg is recommended approximately 30 minutes before sexual activity.
• For managing BPH, a daily dose of 5 mg is typically prescribed.

Side Effects

• Common side effects may include headaches, facial flushing, indigestion (nausea, diarrhea), dizziness, muscle pain, and backaches.
• Occasionally, serious side effects such as sudden vision or hearing loss may occur.

Contraindications

• Avoid combining Tadalafil with nitrates (e.g., nitroglycerin) due to the risk of significant blood pressure drops.
• Contraindicated in patients with severe heart issues, recent heart attacks, or strokes.