Euro-Pharmacies Cialix 20 tabs (20 mg/tab)

Tadalafil – Cialis

Tadalafil is a medication that belongs to a group of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It is known by the trade names Cialis (for the treatment of erectile dysfunction) and Adcirca (for the treatment of pulmonary arterial hypertension).

Here are the characteristics of tadalafil

Mechanism of action

• Tadalafil works by blocking the enzyme phosphodiesterase type 5 (PDE5), which normally breaks down a substance called cyclic guanosine monophosphate (cGMP).
• During sexual stimulation, the release of nitric oxide (NO) in the tissues of the penis increases levels of cGMP.
• This causes relaxation of the smooth muscles of the blood vessels and increased blood flow to the penis, allowing an erection to be achieved and maintained.

Indications

• Tadalafil is primarily used to treat erectile dysfunction (erectile dysfunction) in men.
• It is also used to treat benign prostatic hyperplasia (BPH) and for the treatment of pulmonary arterial hypertension in the form of Adcirca.

Onset of action

• Tadalafil usually has a rapid onset of action, occurring about 30 minutes to 1 hour after taking it.

Duration of action

• The effects of tadalafil can last up to 36 hours, which is why it is often called the “weekend pill.”
• This means that men can achieve an erection for this entire time if they are sexually stimulated.

Dosage

• The usual dosage for treating erectile dysfunction is 10 mg or 20 mg, taken as needed approximately 30 minutes before planned sexual activity.
• For the treatment of BHP, a dose of 5 mg per day is usually used.

Side effects

• Common side effects of tadalafil may include headache, facial flushing, indigestion (e.g., nausea, diarrhea), dizziness, muscle pain, and backache.
• Rarely, serious side effects such as sudden vision loss or hearing loss may also occur.

Contraindications

• Tadalafil should not be taken with nitrates (e.g., nitroglycerin) because of a possible severe drop in blood pressure.
• It is contraindicated in patients with severe heart problems, recent myocardial infarction or stroke.