Eurochem CypioJect 10 ml vial (200 mg/ml)

Testosterone Cypionate

Is a long-acting testosterone formulation prescribed for individuals with very low or absent levels of the hormone, often referred to as Depo testosterone. This Testosterone is esterified, ensuring its prolonged action. Administered via injection, it is usually dissolved in sesame or cottonseed oil and injected into the buttocks, releasing slowly over 7-12 days. The formulation presents as a white milky powder, insoluble in water but easily dispersible in most organic solvents, including vegetable oil.

Pharmacology

The human body naturally produces sex hormones like testosterone, crucial for developing secondary sexual characteristics such as prostate growth, body hair, and alterations in fat and muscle. Testosterone therapy addresses deficiencies that lead to abnormal body growth and sexual development, aiding individuals who lack testosterone or experience infertility.

Indications for Use

Testosterone Cypionate is indicated for conditions characterized by a failure to secrete testosterone, including:

• Primary testicular failure
• Pituitary failure to release Gonadotropins

Bodybuilding

The use of Testosterone and its analogues is widespread among athletes and bodybuilders. This steroid primarily enhances physique and boosts mental acuity. Many bodybuilders report sudden energy bursts and increased aggression, making it popular among weightlifters and wrestlers. Athletes also claim enhanced performance during intense exercises. While Testosterone possesses moderate anabolic properties, it stands out as a potent androgenic agent. The effects of injections are not immediate; users may not observe results for 3-4 weeks. In contrast to oral testosterone, injected formulations remain effective longer. When used over 4-6 weeks, it can boost body mass and protein anabolism, but a calorie-rich diet is essential for muscle-building. Many bodybuilders combine other hormones, as testosterone may convert to estrogen in fat tissues, potentially causing gynecomastia and water retention. To mitigate these risks, bodybuilders often use Arimidex or Tamoxifen during off-cycles. During testosterone therapy, natural testosterone production may be suppressed due to feedback mechanisms inhibiting pituitary LH. High doses can impair spermatogenesis, so it’s advisable to taper off gradually to facilitate recovery of the hypothalamic-pituitary axis. Abrupt cessation can lead to fatigue, weight loss, and increased fracture risk.

Contraindications

Certain individuals should avoid Testosterone Cypionate due to potential aggravations of existing conditions, including:

• Allergy to the drug
• Breast cancer in males
• Prostate cancer in males
• Pregnant or breastfeeding women
• Individuals with liver, kidney, or heart issues

Side Effects

When administered at low doses, side effects of Testosterone Cypionate are uncommon. However, long-term use can lead to reversible side effects, except in cases of virilizing effects in women, which may not be reversible. Common side effects include:

• Nausea, vomiting
• Abdominal cramps, diarrhea
• Swelling
• Libido fluctuations
• Headaches
• Acne, oily skin
• Mood changes like anger, depression, insomnia
• Excessive sweating
• Hair loss
• Gynecomastia

For females, virilizing effects may include:

• Voice deepening
• Hoarseness
• Excess hair growth
• Enlarged clitoris
• Irregular menstrual cycles

Testosterone converts into estrogen, potentially leading to breast enlargement and water retention after extended use.

Overdose

Overdose of Testosterone Cypionate is rare; it is typically injected. While acute side effects are minimal, excessive doses may lead to illness for weeks. Consultation with a healthcare provider is advisable based on the severity of symptoms.

Dosage

In clinical settings, Testosterone Cypionate is delivered via intramuscular injection in strengths of 100 mg/ml and 200 mg/ml. It’s administered every 7-12 days, primarily in the buttock area. Most of the drug binds to proteins with only 2% remaining free, with typical doses ranging from 50 mg to 400 mg per week. Bodybuilders often utilize higher dosages from 200 mg to 400 mg weekly, ensuring a gradual release into the bloodstream.

Control

Testosterone Cypionate is classified as a controlled substance under Class 3 of the Controlled Substance Act, requiring a physician’s prescription in the USA. Unauthorized possession, distribution, or sale is illegal.

Detection

Due to its oily nature, Testosterone Cypionate and its metabolites can remain detectable in urine for 2-3 weeks post-injection. This extended presence influences many bodybuilders to utilize it primarily during off-seasons.

Availability

Most bodybuilders acquire Testosterone Cypionate through the black market; in the USA, the pharmaceutical version is well-regulated and not readily available. Generic alternatives are produced in countries such as Japan, Australia, Mexico, Spain, Brazil, and Thailand. Dosages typically range from 200 mg to 1000 mg weekly, with the price for a 400 mg vial in 2 ml between $20-$40, potentially costing up to $200 monthly. However, product purity and quality often raise concerns, along with the likelihood of counterfeit products.