Genesis Primotest 600 Injection 10 ml vial (600 mg/ml)

Methenolone Enanthate – Primobolan

Primobolan is a well-known and popular steroid as well. Like nandrolone it’s most often used as a base compound for stacking with other steroids. Methenolone however, is a DHT-based steroid (actually, DHB or dihydroboldenone, the 5-alpha reduced of the milder boldenon). Meaning when it interacts with the aromatase enzyme it does not form estrogens at all. That makes it ideal for use when cutting when excess estrogen is best avoided because of its retentive effects on water and fat. Methenolone is mostly only used in such instances, or by people who are very succeptible to estrogenic side-effects, because the anabolic activity of methenolone is slightly lower than that of nandrolone, quite likely BECAUSE it is non-estrogenic.

Because it is a widely available steroid its often used as a replacement for nandrolone or boldenone to those who have no access to Deca-Durabolin or Laurabolin or Equipoise. When stacked with a heavy mass steroid like testosterone and/or methandrostenolone it can deliver almost similar gains. Those seeking to cut will most likely be very pleased stacking it with drostanolone, stanozolol or trenbolone. Women and beginners also stack methenolone WITH nandrolone because this gives a mildly anabolic stack that is generally regarded as one of the safer stacks around in an androgenic perspective. But alas, with the nandrolone, also a very suppressive stack.

Methenolone is available as an injection or as an oral. The injection is naturally regarded as better. Its an enanthate ester which is quite long-acting and only needs to be injected once a week in doses of 300-600 mg. Because it by-passes hepatic breakdown on the first pass, it also has a higher survival rate. The orals are a lot less handy, but often preferred by bodybuilders who are afraid of needles or who are already taking one or more injectable compounds. The tabs are in a short-lived acetate form, meaning that doses of 100-150 mg per day are needed, split over 2 or 3 doses, making the tabs quite inconvenient for use. The reason doses need to be split up, unlike most oral steroids, is because Methenolone is not 17-alpha-alkylated, but 1-methylated for oral bio-availability. This reduces the liver stress, but also the availability, hence the multiple and high doses needed daily.

Like nandrolone, methenolone is very mild on the system. Probably the reason why both are strongly favored as base compounds in stacks. Methenolone has no estrogenic side-effects whatsoever, on account of its structure. Its effects on the cholesterol levels are barely noticeable. In doses of 200 mg or less (injectable) blood pressure is rarely, if at all, altered. As for hepatoxicity, long-term use will of course increase liver values but gradually and only slightly. The injections of course, since they only pass the liver once, have roughly half the liver-toxic effects of the tabs. The low liver-toxicity is accounted for that the bio-availability of methenolone is carried by a 1-methyl-group, which lessens the need for a carrier attachment such as a 17-alpha-akylated group, the main culprit in steroid-related liver afflictions.

The strangest thing however, taking into account that Primo is still a DHT (or rather DHB) derivative, is that it is quite easy on the system androgenically as well. Women use methenolone often, usually the tabs, and find little virilisation symptoms in short term use of methenolone. Long-term use may induce some acne and a deepening of the voice however. Methenolone is also not overly suppressive of the HPT axis (endocrinal axis for the production of natural testosterone). These are both the result of DHB’s 1,2-double bond, which, analog to the parent structure boldenone, reduces the androgenic binding by 50% as opposed to DHT.

For athletes who wish to maintain a “natural” status in competition, the tablets are quite well-suited as detection chances for the acetate-form are quite slim. However tests have improved and quite a number of metabolites1 of methenolone can be detected with a simple urine sample. But an English study documented that there is a liability in eating methenolone contaminated meats2, which could provide a possible defense if found out. One could always claim they ate the meat of a chicken or cow injected with methenolone since the test concluded eating such meat does not improve performance, but can deliver positive tests for several methenolone metabolites almost 24 hours after ingestion. That’s for those of you seeking a viable defense against a possible methenolone-positive.

Stacking and Use

Methenolone comes in orals and injectables. The injectables are to be preferred as they can be used for quite some time and only require injecting once a week. The orals are taking every day, or multiple times a day. An oral passes through the liver twice. An injectable only once. The injectable is more effective since less is broken down.

Methenolone is not used all that often by experienced users. It makes a good product as an alternative to Deca or EQ in a cutting stack, because it has similar properties but does not aromatize and does not have progestagenic activity. But those at least slightly versed will prefer boldenone over methenolone as its more potent gram for gram. Its quite mild, so its not as prone to cause your standard side-effects. This too makes it quite popular with beginners. Methenolone was quite popular during the 70’s in stacks with Methandrostenolone. Some of the all-time greats of bodybuilding were quite fond of this stack.

The common use is similar to that of Nandrolone. 300-400 mg a week, in conjunction with other steroids mostly. Some attempt to make up for the lack of potency switching from nandrolone or boldenone to methenolone by using higher doses, in the neighbourhood of 600-800 mg a week. At that point I feel it would be cheaper to opt for boldenone at 300-400 mg a week though. Methenolone makes a poor stacking partner in mass stacks as both Deca and EQ provide better results while they are qualitatively similar. There is a slight merit in stacking Methenolone with boldenone, because apart from its 1-methyl group, methenolone is basically DHB, the 5-alpha-reduced form of boldenone. But since boldenone itself has very low affinity for 5-alpha-reduction, it should have a good synergistic effect stacking the two at 300 mg/week each.

There is no use for alternate drugs since it does not aromatize, is quite mild and the gains are fairly easy to maintain, so post-cycle use of clomid or Nolvadex is not warranted.

Primobolan depot is a registered trademark of Schering A/G avaiable in 50 mg/cc from Mexico and 100 mg/cc from Europe. It is is the “Cleanest and Gentles” anabolic steroid, will not aromatize, non-toxic, low in androgens.

Primobolan depot may be taken by both Men and Women. Dosages for men are 100-300 mg/week, Women 1/2 dosage. Primobolan depot is the only steroid that works well on a low calorie diet. Effective for bulking, but tends to harden and add muscle tone more that build big muscles.

Primobolan depot works great when added to a cycle (stacked) with other steroids, it tends to lessen water retention and harshness when stacked with more heavy duty testosterone injectables, like Omnadren / Sustanon, Cypoinate / Propionate, ect. It is an analog immune-stimulating steroid used by people with Aids and others with depressed immune systems to build up the immune system and add lean muscle mass. Primobolan is one of the finest steroids in the world today.

Effective Dosage: 100 – 300 mg/week

Description

by Bill Roberts – Primobolan Depot is a Class I steroid working well at the androgen receptor but which apparently is ineffective in non-AR-mediated anabolic effects. It is most closely compared to Deca Durabolin , requiring a little higher dosage to achieve the same anabolic effect, but since it is pleasant to use at doses considerably higher than what is pleasant for nandrolone esters, it can achieve higher maximal effectiveness. That is, provided that one can afford it a gram per week of Primobolan Depot can be costly. 400 mg/week should be considered a reasonable minimum dose.

It appears to cause less inhibition than Deca or testosterone for any given degree of anabolic effect, perhaps because of low CNS activity, lack of conversion to DHT, and lack of aromatization to estrogen. Unlike Deca, it is not metabolically deactivated by 5a-reductase and therefore is not as kind to the skin and hair as that drug. However, when used by itself at modest doses, by suppressing natural testosterone and DHT production, it can improve skin relative to using no anabolic steroids at all.

The half-life is probably about 5 days.

The drug is particularly excellent for use as the last injectable used in a cycle, since for any given anabolic effect it gives much less inhibition than other steroids such as testosterone, nandrolone, or trenbolone . Therefore, residual levels of Primobolan can allow recovery in the taper while still offering useful anti-catabolic or even anabolic support.

Testosterone Cypionate

Is long acting formulation of testosterone which is indicated in the treatment of individuals who have absent or very low levels of the hormone. It is sometimes known as Depo testosterone.

The testosterone is esterified and thus is quite long acting. It is only available in an injection form. The anabolic steroid is typically dissolved in sesame or cotton seed oil and injected into the buttock area. The drug is slowly released from the injection site for about 7-12 days.

The formulation comes as white milky powder and is insoluble in water but freely soluble in most organic solvents including vegetable oil.

Pharmacology

The body normally makes sex hormones like testosterone which is responsible for the normal growth and development of the secondary sexual features. This includes growth of the prostate, testes, penis, scrotum, body hair, vocal cord thickening, alterations in body fat and musculature. When testosterone deficiency occurs, the secondary sexual characteristics and body growth is always abnormal. Thus, one of the indications of testosterone therapy is in the treatment of individuals who lack testosterone or are infertile.

Indications for use

Testosterone Cypionate is used to treat conditions in made where there is a failure of testosterone to be secreted like:

• primary failure of the testes to make the hormone
• failure of the pituitary to release Gonadotropins

Bodybuilding

Testosterone and its analogues are widely used by athletes and bodybuilders. The steroid is taken principally to enhance the body and stimulate the psyche. Most bodybuilders who take this drug claim that it causes spontaneous bursts in energy associated with increased aggression. This feature of the drug is used primarily by weight lifters and professional wrestlers. Many athletes also claim that the drug improves their ability to perform exercise at intense levels.

Testosterone has moderate anabolic properties but also is a powerful androgenic agent.

Because the drug is given by an injection, its effects on the body are not rapid. One may not see any effects for at least 3-4 weeks after starting the injections. Unlike the oral testosterone, the injected formulations last a longer in the body.

When taken for more than 4-6 weeks, it can increase body mass and protein anabolism. However, for the body to build muscle one also has to eat a diet rich in calories. Most bodybuilders also take a combination of other hormones at the same time. Because testosterone is converted to estrogen in the fatty tissues, there is always the chance of developing gynecomastia and water retention. To prevent this, most bodybuilders add Arimidex or tamoxifen during the off cycle.

During testosterone injections, the natural body testosterone release is inhibited by feedback mechanism through inhibition of pituitary LH. At large doses, even spermatogenesis can be impaired. To allow for the hypothalamic-pituitary axis to recover, it is highly recommended that the drug be tapered off slowly over a period of a few weeks. Sudden discontinuation of the drug can lead to extreme fatigue, weight loss and susceptibility to fractures.

Contraindications

There are some individuals who should avoid testosterone like steroids because it can worsen the clinical condition. These conditions include:

• those with allergy to the drug
• males with breast cancer
• males with prostate cancer
• Women who are pregnant or breast feeding
• Individuals who have liver, kidney or heart problems

Side Effects

When Testosterone Cypionate is injected at low doses, the side effects are rare. However, long term use is known to be associated with a varied number of side effects – all of which are reversible when the drug is stopped. For the female who decides to take testosterone, there are virilizing side effects which are not always reversible when the drug is stopped. Like all anabolic steroids, testosterone also has a number of side effects which includes:

• nausea, vomiting
• abdominal cramps, diarrhea
• swelling
• ncreased /decreased libido
• headaches
• acne, oily skin
• mental change including anger, depression, insomnia
• diaphoresis
• loss of hair
• gynecomastia

When taken by females, the drug definitely can cause virilizing effects like:

• deepening of voice
• hoarseness
• excess hair growth
• enlarged clitoris
• irregular menstrual cycles

Testosterone Cypionate is converted into estrogen in the fatty tissues. The estrogen than leads to development of breast enlargement and water retention. This effect is typically seen after the steroid has been used for more than 4 weeks. The gynecomastia does reverse when the steroid is discontinued.

Over dose

Over dose with Testosterone Cypionate is very rare. The drug is usually administered as an injection. If excess dose is injected, there are no acute side effects but the individual may feel sick for a few weeks. Depending on the dose injected, a visit to the hospital or a physician?s office would not be a bad idea.

Dosage

In clinical medicine, Testosterone Cypionate is administered as an injection. The oily suspension is injected only into the muscles. Testosterone Cypionate is available in two strengths 100mg/ml and 200 mg/ml. It is only made for intramuscular injection. The drug can be injected into the buttock area once every 7-12 days. The majority of the Testosterone Cypionate is bound to protein and only 2% is free. The drug is supposed to be injected once a week, but there are some bodybuilders who do inject it every other day.

This is not recommended and can lead to the formation of abscess, sores and skin infections.

The injection site needs to be rotated if the injections are to be continued for a long time. The oily suspension should not be injected into the arms or the abdomen. The dose of Testosterone Cypionate ranges from 50mg-400mg/week, depending on the condition being treated. Bodybuilders tend to inject the higher amount of the drug- 200mg-400mg/week. The drug is then slowly absorbed into the blood stream over the next few days.

Control

Testosterone Cypionate is a controlled substance and classified under class 3 under the Controlled Substance Act. It is only available in the USA with a physician?s prescription. Possession, distribution or sell of this anabolic steroid is considered illegal.

Detection

Anytime an oily suspension of drug is used, the drug does tend to remain in the body for a long time. Testosterone Cypionate and its metabolites can be detected in the urine for as long as 2-3 weeks after the last injection. Because of this long duration in the body, most bodybuilders prefer to take the drug during the off season.

Availability

The majority of bodybuilders get their Testosterone Cypionate from the black market. In the USA the original pharmaceutical product is well controlled and not available for sale. Generic forms of the steroid have been made in Japan, Australia, Mexico, Spain, Brazil and Thailand is all available.

Most bodybuilders use between 200-1000mg/week and a vial of 400mg in 2 ml can cost anywhere from $20-$40. this can easily amount to $200 per month depending on the dose.

However, like all things in cyberspace the purity and quality of the product is always in question. And fakes products are plentiful.

Testosterone Enanthate

Testosterone is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sexual characteristics. The drug can affect the growth of the prostate, testes, seminal vesicles, penis and scrotum and is also important for body growth. Although testosterone is an androgenic hormone, it possesses anabolic properties. Its use has been shown to promote protein synthesis and a positive nitrogen balance in the presence of a rich low calorie diet.

Testosterone also has the ability to cause a slight increase in the production of red blood cells by stimulating the synthesis of EPO from the kidney. This leads to an increase in red blood cells and thus an increase in oxygen carrying capacity.

When testosterone is taken over a long period of time, it inhibits the release of gonadotropins from the pituitary gland through a negative feedback mechanism. At high doses it may even inhibit spermatogenesis.

Testosterone also has the ability to cause a slight increase in the production of red blood cells by stimulating the synthesis of EPO from the kidney. This leads to an increase in red blood cells and thus an increase in oxygen carrying capacity.

When testosterone is taken over a long period of time, it inhibits the release of gonadotropins from the pituitary gland through a negative feedback mechanism. At high doses it may even inhibit spermatogenesis.

Dosage

Testosterone enanthate (Delatestryl) only dissolves slowly after an intramuscular injection and therefore it should not be taken more than 1-2 times per month. The formulation comes as an esterified preparation of testosterone which is only meant to be administered by an intramuscular injection. The esterification of testosterone increases the duration of action of the testosterone. The preparation goes into a colourless to slightly yellow suspension of sesame oil. For medical applications, a dose of 250-500mg is used once a month.

Indications

Delatestryl is indicated in the treatment of conditions where testosterone is either deficient or absent. These conditions include:

• primary hypogonadism, where the testes have been injured and do not make the testosterone
• hypogonadism due to failure of the pituitary gland to release gonadotropins
• delayed puberty

In women with breast cancer, testosterone can help block the effect of estrogen and prevent further spread. It is an option instead of surgical removal of the ovaries.

In most cases of testosterone deficiency, therapy is required for a long time until the secondary sexual characteristics have been characteristically developed and growth is adequate.

Duration

Treatment of all individuals with testosterone anthate depends on age, sex, diagnosis and response to treatment and the occurrence of side effects. In general, the drug is well tolerated when prescribed as recommended. Delatestryl should always be injected into the gluteal muscles and not simply under the skin. The injection site should be rotated to prevent abscess formation. Another option is to inject the drug on the outside of the thigh. The drug should never be administered intravenously.

The dose of testosterone enanthate should not exceed 1000 mg per month because the drug has prolonged activity. It is extremely rare to give this drug once every fortnight. The drug should always be checked before injection. It is usually a colourless yellow suspension is clear. Particles or clumping indicates that the product has expired or is inactive. The duration of treatment varies from 4-6 months.

The drug should be stored at room temperature.

Bodybuilders

Many bodybuilders use Delatestryl during the off-season. The drug remains in the body for a long time and it is advisable not to use it during the active sports season. The drug definitely has anabolic and androgenic properties. However, the effects of the drug are not immediate and may take at least 3-4 weeks to become visible. Many bodybuilders also use other anabolic hormones such as GH/thyroxine in combination.

Because testosterone also converts to estrogen in fat tissue, many bodybuilders develop breast enlargement and store water. The dose used to increase muscle mass and strength is about 250-1000 mg/week. However, at the higher doses the drug has potent side effects and it is strongly recommended that all beginners start off with the low dose.

The increase in protein mass is gradual, but does not occur. Because the steroid also stimulates red blood cell production, many bodybuilders also find that they have an increased ability to perform under intense training conditions. Testosterone enanthate is preferred by most bodybuilders because it is readily available and has a number of benefits. It promotes health, increases athletic performance and leads to a positive nitrogen balance. There are reports that it also selectively reduces fat and increases muscle mass. Recent studies from the World Sport Agencies show that this particular drug can boost performance, increase muscle mass and still not be detected in the urine within the first few weeks. Even though the anabolic effects are not obvious, most people have noticed an increase in strength. Sometimes the water retention can be very dramatic and some individuals take a diuretic pill to remove it. To prevent breast enlargement, testosterone antanthate is cycled with drugs such as Arimidex or Tamoxifen. Most people take the testosterone for 4-6 weeks and then stop for a few weeks. During this phase, you can wash out with Arimidex.

Women

All testosterone analogues have the potential to cause virilizing effects if the duration of use is prolonged. In women, these virilizing signs can be deepened by speech, excessive hair growth, irregular menstruation, mood swings and enlargement of the clitoris. It is recommended that at the first sign of virilizing symptoms the drug should be stopped. The reason for this is that some of the virilizing signs may not be reversible even after stopping the steroid.

Side effects

Like all anabolic steroids, testosterone antanthate has a few side effects. These side effects are generally mild and well tolerated. The majority of people see that some side effects after 3-4 months of therapy. The most common side effects are:

• bleeding irregularities
• virilizing effects
• deepening of the voice
• enlargement of the clitoris
• gynaecomastia
• painful erections
• hair loss, acne oily skin
• retention of body water
• nausea, vomiting, jaundice
• liver cancer (rare)
• mental changes, depression, headaches, anxiety,
• increased serum cholesterol

While most of these side effects are reversible, the breast enlargement and some virilising effects are not. The concurrent use of oestrogens to reduce the side effects of virilisation is not always helpful.

In children, the use of testosterone must be closely monitored. It may accelerate bone maturation but does not increase compensatory linear growth – resulting in abnormal body distortion in the anatomy-esp. Jaw and face.

Warnings

The drug should be used very cautiously in people with:

• breast cancer and hypercalcaemia
• liver dysfunction
• prostate cancer
• heart problems

There have been isolated reports of individuals developing a dry cough, breathing difficulties after injection with Testosterone enanthate. This has been linked to the oil preparation or an impurity in the formulation.

All individuals using testosterone should have their liver enzymes and blood haematocrit checked regularly to ensure that they are within normal limits.

Recognition

Testosterone enanthate has a very long half-life in the body. For this reason, it is also detected in the urine long after it has been discontinued. Current techniques of testing can identify testosterone or its metabolites in the urine at least 3-4 weeks after the drug has been stopped. Infact, testing has also gone beyond urine tests. If the excessive use of testosterone is suspected, one can even detect traces of testosterone in the hair 2-4 months after the drug has been stopped.

However, one should know that the tests today testosterone anthate is not perfect. About 50% of people who take this steroid are missed based on testosterone / epitestosterone ratios.

Cost

The legal testosterone anthate is quite difficult to keep off. The majority of bodybuilders get their testosterone from the black market. Generic testosterone formulations in Europe and Mexico are widely available. The drug is not cheap and a vial of 250 mg can cost anywhere from $10-$20. Over the last 2 decades, the increasing scrutiny of these drugs by the DEA has led to unscrupulous dealers selling fake or counterfeit products. So in the end, it’s always up to the buyer.