Hilma Biocare Nandrolone Phenylpropionate 10 ml vial (100 mg/ml)

Nandrolone Phenylpropionate

Nandrolone Phenylpropionate is a highly effective injectable anabolic steroid that closely resembles Deca-Durabolin, which utilizes the slower-acting nandrolone decanoate. The key distinction lies in the release time into the bloodstream; while its counterpart provides a sustained release lasting around three weeks, Nandrolone Phenylpropionate remains active for roughly one week. This allows Deca-Durabolin to require injections every 2-3 weeks, whereas Nandrolone Phenylpropionate necessitates administration every few days to weekly. Both steroids share a reputation among athletes and bodybuilders for enhancing strength and promoting lean muscle mass without the prominent estrogenic or androgenic side effects.

Structural Characteristics

Nandrolone Phenylpropionate features a modified structure with a propionic phenyl ester linked to the 17-beta hydroxyl group, resulting in a less polar and more slowly absorbed compound post-injection. Upon entering the bloodstream, the ester detaches to release free (active) nandrolone, prolonging therapeutic effects and allowing for a less frequent injection schedule. The drug triggers a rapid increase in nandrolone levels within 24 to 48 hours after deep intramuscular injection, tapering off to baseline within one week.

Side Effects (Estrogenic)

Nandrolone exhibits a low conversion rate to estrogen, approximately 20% that of testosterone, due to limited conversion in active steroid aromatization sites like adipose tissue. While estrogen-related side effects are minimized, higher dosages may still lead to issues such as water retention, body fat gain, and gynecomastia. To combat these potential side effects, using anti-estrogens like clomiphene citrate or tamoxifen citrate can be effective. An alternative is employing aromatase inhibitors like Arimidex (anastrozole), which can be costly but more effectively prevent estrogen synthesis. It’s essential to note that nandrolone displays some progestin activity, causing effects similar to estrogen and enhancing fat storage and mammary tissue growth. Consequently, the use of anti-estrogens may help manage gynecomastia related to nandrolone.

Side Effects (Androgenic)

Although categorized as an anabolic steroid, nandrolone can impose androgenic side effects at higher doses, such as oily skin, acne, and increased body/facial hair. Male pattern hair loss may also intensify. Women may experience virilization, which includes voice deepening, menstrual changes, and facial hair growth. Despite relatively lower androgenic activity than steroids like testosterone, nandrolone can still suppress libido in males when administered without supplementary androgen.

Side Effects (Hepatotoxicity)

Nandrolone is not 17-alpha alkylated, demonstrating no known hepatotoxicity in healthy individuals.

Side Effects (Cardiovascular)

Anabolic/androgenic steroids can detrimentally affect cholesterol levels, decreasing HDL (good) cholesterol and increasing LDL (bad) cholesterol, ultimately raising the risk for arteriosclerosis. Research shows that a weekly administration of 600mg nandrolone decanoate for ten weeks can lead to a 26% decline in HDL levels. Though this is a harsher effect compared to testosterone enanthate, nandrolone still poses a lesser risk to serum lipids than 17-alpha alkylated steroids. These compounds can influence blood pressure, triglycerides, and endothelial function, raising cardiovascular disease risks.

Side Effects (Testosterone Suppression)

All anabolic/androgenic steroids, particularly in doses promoting muscle gain, suppress natural testosterone production. Studies indicate that 100mg of nandrolone decanoate weekly for six weeks led to a 57% decrease in testosterone levels, escalating to 70% at 300mg weekly. Nandrolone’s progestational nature significantly contributes to this suppression. Recovery to normal testosterone levels post-therapy typically occurs within 2 to 6 months, although abuse may precipitate long-term hypogonadotrophic hypogonadism requiring medical attention.

Administration (Men)

For optimal anabolic effects, initial guidelines suggested dosages ranging from 25 to 50mg weekly for 12 weeks. Performance-enhancing doses range from 200 to 400mg weekly, administered in 8 to 12-week cycles, allowing users to observe notable gains in muscle mass and strength. Due to its rapid action, weekly dosages are usually divided into two injections.

Administration (Women)

For general anabolic purposes, dosages of 25 to 50mg per week for 12 weeks were historically recommended. Women seeking performance enhancements typically use 50mg weekly via a single injection for cycles lasting 4 to 6 weeks. It’s advisable to avoid increased doses or prolonged usage to minimize the risk of androgenic side effects. Even with low androgenicity, women may still encounter virilization symptoms, and discontinuation of nandrolone phenylpropionate is essential to prevent lasting changes.