LA Pharma Sildenafil 10 tabs (100 mg/tab)

Sildenafil

Sildenafil is a renowned medication classified as a phosphodiesterase type 5 (PDE5) inhibitor, famously marketed under the brand name Viagra.

Mechanism of Action

• Sildenafil inhibits the enzyme phosphodiesterase type 5 (PDE5), preventing the breakdown of cyclic guanosine monophosphate (cGMP). This action enhances nitric oxide (NO) release during sexual arousal, elevating cGMP levels, promoting smooth muscle relaxation in blood vessels, and boosting blood flow to the penis.
• This process facilitates the achievement and maintenance of an erection.

Indications

• Sildenafil primarily addresses erectile dysfunction in men.
• It can also be prescribed under the name Revatio for managing arterial hypertension.

Onset of Action

• The onset of sildenafil typically occurs within 30 minutes post-ingestion, although some individuals may experience effects after up to 1 hour.

Duration of Action

• Effects last approximately 4 to 5 hours, providing a sufficient window for sexual activity.

Dosage

• The recommended starting dose is 50 mg, adjustable based on individual response and requirements.
• It is advisable to take sildenafil about 30 minutes to 1 hour prior to sexual activity.

Side Effects

• Common side effects may include headache, facial flushing, dyspepsia (e.g., nausea, diarrhea), visual disturbances (e.g., blurred vision, color vision changes), elevated blood pressure, and in rare cases, alterations in hearing.

Contraindications

• Combining sildenafil with nitrates (e.g., nitroglycerin) is prohibited due to the risk of severe hypotension. It is also contraindicated for individuals with serious heart conditions or those who have recently experienced a heart attack or stroke.