Somatrop-Lab Nandrolone Phenylpropionate 10 ml vial (100 mg/ml)

Nandrolone Phenylpropionate

Nandrolone phenylpropionate is an injectable anabolic steroid closely resembling Deca-Durabolin, which employs the slower-release nandrolone decanoate. The main distinction lies in the release rate: while nandrolone decanoate remains active for about 3 weeks, nandrolone phenylpropionate is effective for just one week. Clinically, Deca-Durabolin can be injected every 2 to 3 weeks, whereas Durabolin requires administration every few days to weekly. Athletes and bodybuilders highly value both for promoting strength and lean muscle gains with minimal estrogenic or androgenic side effects.

Structural Characteristics

Nandrolone decanoate features a modified structure with the propionic phenyl ester attached to the 17-beta hydroxyl group. Esterified steroids are less polar and absorbed more slowly from the injection site. Once in the bloodstream, the ester detaches, providing active nandrolone. This allows nandrolone phenylpropionate to produce a rapid increase in nandrolone levels within 24 to 48 hours post-injection, tapering to baseline within a week.

Side Effects (Estrogenic)

Nandrolone has a minimal tendency to convert to estrogen, estimated at about 20% of testosterone’s conversion rate. This is due to its reduced aromatization in adipose tissue. However, elevated estrogen levels can occur at higher dosages, leading to side effects like water retention, fat gain, and gynecomastia. To mitigate these effects, anti-estrogens like clomiphene citrate or tamoxifen citrate may be necessary, or aromatase inhibitors like Arimidex, although these can be costly and negatively affect blood lipids.

Progestin Activity

Nandrolone exhibits some progestin activity, potentially causing side effects similar to estrogen, such as inhibiting testosterone production and increasing fat storage. Progestins can enhance the effects of estrogens on mammary tissue, leading to gynecomastia even in the presence of low estrogen levels. Utilizing an anti-estrogen often suffices to combat these side effects.

Side Effects (Androgenic)

As an anabolic steroid, nandrolone can still induce androgenic side effects, particularly at higher dosages, such as oily skin, acne, and hair growth. Women face potential virilizing effects including voice deepening and menstrual changes. Nandrolone’s lower androgenic activity means a higher dose is needed to experience strong androgenic effects compared to testosterone or methandrostenolone. However, it may suppress libido in males due to its mild androgenicity and testosterone suppression.

Side Effects (Hepatotoxicity)

Nandrolone is not c-17 alpha alkylated, indicating it generally lacks hepatotoxic effects in healthy individuals.

Side Effects (Cardiovascular)

Anabolic steroids may negatively affect cholesterol levels, reducing HDL and raising LDL, which can elevate arteriosclerosis risk. Research shows that administering 600mg of nandrolone decanoate weekly can cause a 26% drop in HDL, more than testosterone enanthate at the same dose. Overall, nandrolone decanoate holds a lesser impact on serum lipids compared to c-17 alpha alkylated steroids, but various factors influence its overall cardiovascular effects.

Side Effects (Testosterone Suppression)

Like all anabolic steroids, nandrolone suppresses endogenous testosterone production, with studies indicating a 57% reduction in testosterone levels after 100mg weekly for 6 weeks and 70% at 300mg. Its progestational activity significantly affects testosterone synthesis, which can lead to prolonged recovery issues without testosterone-stimulating interventions.

Administration (Men)

For anabolic effects, early guidelines suggested 25 to 50mg weekly for 12 weeks. Performance-enhancing users typically take 200 to 400mg weekly, in cycles of 8 to 12 weeks, enabling noticeable gains in lean muscle and strength; the dosage is usually split into two injections per week.

Administration (Women)

Guidelines also recommend 25 to 50mg weekly for women over 12 weeks for general anabolic benefits. Most common for performance enhancement is a single 50mg injection weekly over 4 to 6 weeks. Higher doses and extended use may lead to virilizing effects, requiring immediate cessation to avoid permanent changes.