Sopharma Tamoxifen 30 tabs (10 mg/tab)

Tamoxifen – Nolvadex

Nolvadex, a non-steroidal medication, showcases remarkable anti-estrogen characteristics. By attaching to estrogen receptors, it effectively hinders estrogen’s impact. This treatment is approved for certain types of breast cancer in both women and men and is utilized in preventing breast cancer in women at high risk after experiencing ductal carcinoma in situ. Additionally, Nolvadex is under investigation for various breast cancer types and is commonly known as Tamoxifen or Tamoxifen Citrate.

Indications

Nolvadex is administered for treating metastatic breast cancer in both genders, especially effective in premenopausal women with this condition. As a preferred alternative to surgery or radiation, it benefits patients with estrogen receptor-positive tumors significantly. Moreover, Nolvadex serves as adjuvant therapy for women post-surgery.

Dosage

This medication is accessible in 10 mg and 20 mg pills as well as a 10 mg solution. The standard dosage is 20 mg daily, taken orally and well-absorbed, either with or without food. Patients diagnosed with breast cancer typically receive dosages ranging from 20 to 40 mg daily, split into 1-3 doses for amounts exceeding 20 mg. Many bodybuilders start at 20 mg daily, occasionally increasing to 30 mg, but long-term therapy beyond five years is generally inadvisable.

Bodybuilders

While Nolvadex does not exert direct anabolic or androgenic effects, its efficacy stems from blocking estrogen receptors. This blockade induces a response from the hypothalamus, signaling diminished sex hormone, prompting an increase in Gonadotropins (LH and FSH), which subsequently raises testosterone synthesis. Consequently, the testosterone surge contributes to Nolvadex’s anabolic and androgenic effects. Bodybuilders often employ Nolvadex post-anabolic steroid cycles to counteract testosterone suppression. While its effects mirror those of Arimidex, Nolvadex effectively curbs estrogen activity, helping prevent gynecomastia and water retention. Notably, concrete weight gain with Nolvadex alone is uncommon, yet its role during washout cycles is crucial for sustaining gains and aiding testicular recovery.

Women

Nolvadex is frequently prescribed for women battling metastatic breast cancer. Regardless of its usage – medically or in bodybuilding – women should be monitored by a healthcare provider. Side effects that warrant attention include:

• vaginal bleeding
• new breast lumps
• lower abdominal fullness
• pelvic pain
• leg swelling
• shortness of breath (sudden or gradual)
• vision changes
• irregular menstrual cycles

Regular breast examinations with healthcare professionals are crucial, even though significant complications are rare. Female bodybuilders should note that Nolvadex may hinder the efficacy of birth control pills.

Overall Side Effects

Recognized as a safe drug, Nolvadex has treated thousands of women, with significant side effects occurring in merely 1-3% of cases. Rarely do patients discontinue treatment due to adverse effects. The most frequent side effects in both genders include:

• hot flashes
• leg swelling
• altered taste
• genital itching
• depression
• dizziness
• headaches
• hair loss
• vaginal dryness
• nausea and vomiting
• bone pain
• coughing
• abdominal cramps
• loss of appetite

Most of these symptoms resolve upon ceasing the drug.

Warnings

Nolvadex may induce hypercalcemia in breast cancer patients shortly after initiation. There have also been concerns regarding uterine cancer linked to Nolvadex use.
Nolvadex can potentially lead to blood clots that might travel to the lungs. Rare complications such as liver cancer and vision changes have also been documented.

Overdose

Nolvadex is exceptionally safe, with overdose cases being virtually non-existent. Should excessive pills be taken, effects may not manifest until 4-6 days later. Symptoms such as tremors, unsteady gait, dizziness, or irregular heart rate may arise. Supportive treatment generally suffices, and permanent toxicity is not observed.

Detection

This drug is frequently screened by numerous sports organizations. While women may possess prescriptions for Nolvadex, males testing positive are prohibited from future competition. Its presence and metabolites can remain detectable in urine for 3-4 weeks post-administration.

Cost

Nolvadex is regularly accessible but varies in price, averaging between $1.50 and $2.00 per pill. Although generic versions from Asia may offer lower costs, their quality and purity remain questionable. Currently, there are no known counterfeit products for Nolvadex.