Sterling Knight Clomiphene Citrate 60 tabs (50 mg/tab)

Clomiphene Citrate – Clomid

Clomiphene citrate (Clomid) is a synthetic, non-steroidal medication structurally akin to estrogen, primarily utilized as an ovulatory stimulant. It binds to estrogen receptors in the hypothalamus, inhibiting the perception of actual estrogen and prompting the pituitary gland to release increased levels of gonadotropins, such as FSH and LH, which stimulate the ovaries or testes to produce more estrogen or testosterone.

This action is beneficial in treating women with ovarian failure and inducing ovulation. However, prolonged use may heighten the risk of ovarian cancer.

Pharmacology

Clomid is advised for women experiencing ovulatory dysfunction. Many women struggling to conceive face issues in their ovulation cycle, including those affected by polycystic ovarian syndrome or unexplained amenorrhea. A detailed evaluation of the menstrual cycle is essential prior to prescribing Clomid. Accurate timing is crucial for ovulation, requiring monitoring of temperature and blood tests.

Clomid treatment generally commences around the 5th day of the cycle and is usually administered for 3-6 cycles, with long-term therapy discouraged.

Mode of Action

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Indications

Clomid is indicated for women with confirmed ovulatory dysfunction, provided they meet these criteria:

• Not pregnant at the time of treatment.
• No ovarian cysts, confirmed via ultrasound.
• No abnormal vaginal bleeding necessitating thorough examination.
• Normal liver function tests.
• While Clomid may be used in female infertility, studies are limited regarding its effects for men. Nevertheless, reports indicate potential benefits for treating male fertility issues, but long-term safety remains uncertain.

Clomiphene is a large, odorless molecule, typically available in 50 mg tablet form and dissolves in various organic solvents.

Prior to treatment, patients must undergo comprehensive evaluations for any gynecological and endocrine disorders. Ovulation generally occurs within 5-10 days after beginning Clomid, and timely intercourse should align with the anticipated ovulation window.

Initial dosing starts at 50 mg/day for 5 days, with possibles adjustments if ovulation does not occur.

Body Building

Clomid is also misused by athletes, both amateur and professional, who commonly abuse a variety of substances including anabolic steroids and HCG. Unlike other anabolic agents, Clomid elevates testosterone levels by increasing LH, rather than suppressing them.

Most anabolic steroids exhibit both androgenic and anabolic traits, some even possessing estrogenic activity, which can result in gynecomastia. Athletes often use Clomid to inhibit this condition by blocking estrogen receptors, thereby preventing breast enlargement while enhancing testosterone production.

Clomid Dosage for Athletes

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Long-term effects of Clomid remain unknown, and its usage for extended periods should be avoided.

Side Effects

At prescribed doses and durations, Clomid is generally safe, with most side effects being transient. Common side effects may include:

• Flushing
• Abdominal discomfort
• Nausea and vomiting
• Breast tenderness
• Headaches
• Abnormal vaginal bleeding
• General fatigue
• Hair loss
• Visual disturbances

Due to its action on the brain, there’s concern regarding long-term visual side effects caused by pituitary gland enlargement, potentially leading to visual impairment or changes. Most cases tend to resolve upon discontinuation of Clomid. Immediate cessation is advised if vision changes arise, along with consultation with an ophthalmologist.

Mood Changes

Mood swings are another reported side effect, with numerous cases of behavioral disturbances such as depression, anger, anxiety, and aggression noted in prolonged users. Reports of paranoia, restlessness, and insomnia have also surfaced. Despite these concerns, clinical trials indicate that serious side effects affect fewer than 1% of women.

Cost

Although Clomid requires a prescription for infertility treatment, it is readily available online without one. Prices for 100 pills (25-50 mg) typically range from $50-100.

Levels

The availability of Clomid is widespread, but it’s banned by all major sports organizations. Its metabolites can be detected in urine for 5-12 days post-use. Advanced testing methods exist to monitor testosterone and estrogen levels, thereby flagging potential abuse.

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