Sterling Knight Nandro-Phenyl 10 amps (10x 100 mg/ml)

Nandrolone Phenylpropionate

Nandrolone phenylpropionate is a potent injectable anabolic steroid, exhibiting properties akin to Deca-Durabolin, which utilizes the longer-acting nandrolone decanoate. The key distinction lies in the release rate: while nandrolone decanoate remains effective for approximately 3 weeks, nandrolone phenylpropionate operates within a shorter timeframe of about one week. Clinically, this means Deca-Durabolin can be administered bi-weekly, whereas Nandrolone Phenylpropionate typically calls for injections every few days to weekly. Both steroids are nearly interchangeable, but athletes and bodybuilders often favor Deca-Durabolin for its ability to enhance strength and promote lean muscle gains with minimal estrogenic or androgenic side effects.

Structural Characteristics

Nandrolone phenylpropionate is structurally modified with a propionic phenyl ester attached to the 17-beta hydroxyl group. This esterification results in diminished polarity and slower absorption from the injection site. Upon entering the bloodstream, the ester is detached, releasing free nandrolone. The compound offers a rapid release spike in nandrolone levels approximately 24 to 48 hours post-injection, tapering to baseline within a week.

Side Effects (Estrogenic)

This steroid exhibits a low rate of estrogen conversion, estimated at only 20% of that seen with testosterone. Although nandrolone can be converted to estradiol in the liver, its conversion in adipose tissue is considerably less, reducing estrogen-related side effects. However, higher doses could still elevate estrogen levels, leading to water retention, body fat increase, or gynecomastia. In such cases, an anti-estrogen like clomiphene citrate or tamoxifen citrate may be necessary. Alternatively, aromatase inhibitors such as Arimidex (anastrozole) can effectively manage estrogen levels but may be more costly and have adverse effects on blood lipids.

Additionally, nandrolone possesses progestin activity, with a heightened affinity for progesterone receptors, leading to side effects analogous to estrogen, such as testosterone suppression and increased fat storage rates. The synergistic interaction between progestins and estrogens can also contribute to gynecomastia, necessitating anti-estrogen intervention to control symptoms effectively.

Side Effects (Androgenic)

Despite being categorized as an anabolic steroid, possible androgenic side effects can occur, particularly at elevated doses. Users might experience oily skin, acne, and excessive hair growth, including male pattern baldness. Women are cautioned about virilizing effects, which could manifest as voice deepening, menstrual irregularities, skin texture changes, facial hair growth, and clitoral enlargement. Notably, nandrolone has lower androgenic activity compared to testosterone, meaning users are less likely to experience strong androgenic side effects unless dosages are significantly high. However, potential libido reduction in males should not be overlooked when not supplemented with additional androgens.

In target tissues sensitive to androgens, nandrolone’s androgenicity can be diminished via conversion to dihydronandrolone (DHN) through the 5-alpha reductase enzyme. The use of 5-alpha reductase inhibitors like finasteride alongside nandrolone may enhance androgenic side effects, thus should be avoided if low androgenicity is desired.

Side Effects (Hepatotoxicity)

Nandrolone is not classified as c-17 alpha alkylated, making liver toxicity unlikely among healthy users.

Side Effects (Cardiovascular)

Anabolic/androgenic steroids can negatively impact cholesterol levels, diminishing HDL (good) cholesterol and increasing LDL (bad) cholesterol, elevating the risk of arteriosclerosis. Various factors, including dosage, administration route, and steroid type, influence their effects on serum lipids. For instance, a study on 600mg of nandrolone decanoate weekly for 10 weeks showed a 26% HDL reduction, slightly surpassing testosterone enanthate’s effects. Moreover, nandrolone decanoate may display a greater adverse impact on the HDL/LDL ratio compared to testosterone cypionate, yet it still poses less threat than c-17 alpha alkylated agents. Other cardiovascular risks may include heightened blood pressure, triglyceride levels, and support for left ventricular hypertrophy.

Side Effects (Testosterone Suppression)

All anabolic/androgenic steroids are known to suppress endogenous testosterone levels when employed at doses conducive to muscle growth. A study with 100mg weekly of nandrolone decanoate for 6 weeks revealed about a 57% drop in serum testosterone, climbing to 70% at 300mg per week. The progestational properties of nandrolone can significantly contribute to this suppression, despite its reduced estrogen conversion potential. Depending on the individual, normalization of testosterone levels can occur 2 to 6 months post-therapy, although extended hypogonadotropic hypogonadism arising from steroid use may necessitate medical intervention.

Administration (Men)

For optimal anabolic effects, initial guidelines recommend doses of 25 to 50mg weekly over 12 weeks. Common practice for physique or performance enhancement ranges from 200 to 400mg weekly, applied in cycles of 8 to 12 weeks. This dosage typically yields noticeable improvements in lean muscle and strength. Given the fast-acting nature of the phenylpropionate ester, the weekly total is generally divided into two doses, spaced evenly.

Administration (Woman)

For general anabolic purposes, the initial dosage guideline mirrors that for men, at 25 to 50mg weekly for 12 weeks. For physique enhancement, 50mg weekly via a single injection is prevalent, spanning a cycle of 4 to 6 weeks. Increased doses or longer usage periods are discouraged due to the risk of androgenic side effects. Although only mildly androgenic, women can still experience virilization symptoms; immediate discontinuation is advised to mitigate any potential permanent changes.