Sunrise Extra Super Tadarise 100 tabs (40 + 60 mg/tab)

Tadalafil – Cialis

Tadalafil, a member of the PDE5 inhibitors class, is commonly marketed as Cialis for treating erectile dysfunction and as Adcirca for addressing pulmonary arterial hypertension.

Mechanism of action

• Tadalafil inhibits the enzyme PDE5, which degrades cGMP.
• With sexual stimulation, enhanced levels of nitric oxide elevate cGMP.
• This facilitates blood vessel relaxation, improving blood flow to the penis, which assists in achieving and sustaining an erection.

Indications

• Tadalafil is predominantly prescribed for erectile dysfunction.
• It also treats benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension.

Onset of action

• The action of tadalafil typically begins within 30 to 60 minutes of administration.

Duration of action

• The efficacy of tadalafil can persist for up to 36 hours, earning it the nickname “weekend pill.”
• Men can maintain an erection throughout this period with adequate sexual stimulation.

Dosage

• For erectile dysfunction, the common dosage is 10 mg or 20 mg taken about 30 minutes before engaging in sexual activity.
• For managing BPH, a standard daily dosage of 5 mg is recommended.

Side effects

• Typical side effects of tadalafil include headache, facial flushing, indigestion, dizziness, backache, and muscle pain.
• In rare instances, severe effects like sudden vision or hearing loss may occur.

Dapoxetine

Dapoxetine is a medication designed for the treatment of premature ejaculation, marketed as Priligy.

Mechanism of action

• Dapoxetine is classified as a selective serotonin reuptake inhibitor (SSRI).
• It functions by inhibiting the reuptake of serotonin, enhancing its availability in the brain.
• This increase in serotonin contributes to better control over ejaculation.

Indications

• Dapoxetine is primarily effective in treating premature ejaculation in men.
• It is suitable for men aged 18 to 64 experiencing rapid ejaculation issues.

Onset of action

• The onset of dapoxetine occurs rapidly, typically within 1 to 2 hours post-ingestion.

Duration of action

• The effects of dapoxetine generally last between 4 to 24 hours, varying based on dosage and patient response.

Dosage

• The standard dose for dapoxetine ranges from 30 mg to 60 mg as needed.
• The initial suggested dose is often 30 mg, adjustable by a healthcare provider.

Side effects

• Common adverse reactions to dapoxetine include headache, dizziness, dry mouth, nausea, fatigue, and drowsiness.
• Infrequently, hot flashes, increased anxiety, behavioral changes, or altered sexual function may occur.

Contraindications

• Dapoxetine is contraindicated for patients with severe hepatic or renal issues, serious heart conditions, epilepsy, bipolar disorder, or those on MAO inhibitors.
• Combining dapoxetine with alcohol is discouraged due to heightened side effect risks.