Swiss Healthcare Clomiphene 60 tabs (50 mg/tab)

Clomiphene Citrate – Clomid

Clomiphene Citrate (Clomid) is a synthetic, non-steroidal medication resembling the structure of estrogen. It functions primarily as an ovulatory stimulant, leveraging its affinity for estrogen receptors in the hypothalamus. This interaction disrupts the hypothalamus’ perception of actual estrogen levels, prompting increased release of Gonadotropins such as FSH and LH from the pituitary gland. These hormones then stimulate the ovaries or testes to enhance production of estrogen or testosterone.

This mechanism is pivotal for treating women experiencing ovarian failure and those needing ovulation induction. However, long-termuse may raise ovarian cancer risks.

Pharmacology

Clomid is prescribed for women with ovulatory dysfunction who have difficulty conceiving, often due to conditions like polycystic ovarian syndrome or unidentified amenorrhea sources. Thorough menstrual cycle evaluations determine the specific issues impacting ovulation. The ovulation process requires meticulous timing, involving tracking basal body temperature and conducting blood tests.

Typically, Clomid is administered on the 5th day of the menstrual cycle for 3-6 cycles, with extended therapy discouraged.

Mode of Action

This powerful drug’s effect allows it to mimic estrogen action. By blocking estrogen receptors in the hypothalamus, it creates an illusion of low estrone levels, stimulating Gonadotropin production, which in turn promotes ovary functionality and leads to elevated estrogen synthesis. This surge is critical for successful fertilization.

Indications

• The female patient must not be pregnant.
• Ovarian cysts must be ruled out via ultrasound.
• Absence of vaginal bleeding is necessary; an examination is required if bleeding occurs, to exclude potential malignancy.
• Patients should present normal liver function tests.
• While beneficial for female ovulatory issues, Clomid’s efficacy in addressing male infertility is less established. Nonetheless, some success in enhancing LH and FSH leading to improved sperm count has been documented in isolated cases.
• Prescription dosage is crucial for infertility management.

Clomiphene is a large, odorless compound, soluble in organic solvents and available as a 50 mg tablet.

Thorough exploration of gynecological and endocrine disorders is mandatory prior to Clomid administration, with ovulation expected within 5-10 days of initiation. Timing of intercourse is critical to align with ovulation.

The standard starting dosage is 50 mg/day for 5 days, adjustable for those not achieving ovulation.

Body Building

Clomid garners popularity among athletes and bodybuilders aiming to counteract the estrogen effects of anabolic steroids. Unlike other steroids, Clomid elevates testosterone levels by stimulating LH production without suppression. Its use is primarily for the prevention of gynecomastia, a common side effect of anabolic steroids.

By inhibiting estrogen receptors, Clomid facilitates an increase in LH and FSH, further enhancing testosterone synthesis from the testes, providing an additional athletic advantage. Bodybuilders may employ it solely for its anabolic benefits or alongside other steroids or growth hormones.

Clomid Dosage for Athletes

Typically taken once daily, Clomid should be used alone or with low-potency anabolic steroids. Athletes often transition to Clomid post-steroid cycle to boost testosterone production and prevent gynecomastia. Initiation of Clomid is recommended within 7-10 days after steroid cessation.

Dosage varies, with most bodybuilders consuming 50-100 mg/day for two weeks, with some suggesting an increase to 100 mg/day if results are lacking. Use should cease after three weeks, as outlined by cycling protocols developed by previous users. Consultation from fertility experts is advisable for accurate advice, as medical guidance for bodybuilding purposes remains scarce.

The long-term usage of Clomid is generally discouraged, though exact parameters are undefined.

Side Effects

Short-term, Clomid use is mostly safe; transient adverse reactions cease upon treatment conclusion.

• Flushing
• Abdominal discomfort
• Nausea and vomiting
• Breast tenderness
• Headaches
• Abnormal vaginal bleeding
• General fatigue
• Hair loss
• Visual disturbances

Concerns arise due to its action on the hypothalamus; prolonged use may lead to pituitary enlargement, risking visual changes that could impair driving or machinery operation. Immediate cessation and ophthalmological consultation are advised upon experiencing vision alterations.

Mood Changes

Another prominent side effect involves mood variations, including severe depression, anxiety, and aggression, particularly after extended use. Although concerning, such effects are reported in less than 1% of female users; data on male bodybuilders remains limited.

Cost

While Clomid requires a physician’s prescription for infertility treatment, it is available online without one. Costs vary, ranging from $50-$100 for 100 pills (25-50 mg).

Levels

Clomid remains accessible but is banned in professional sports. Detection persists in urine for 5-12 days post-use, with advanced testing measures determining testosterone and estrogen ratios indicative of potential abuse.