Ajanta Apcalis Oral Jelly 1 sachet (20 mg/sachet)

Tadalafil – Cialis

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, primarily marketed as Cialis for erectile dysfunction and as Adcirca for pulmonary arterial hypertension.

Discover the key features of Tadalafil:

Meccanismo d'azione

• Tadalafil inhibits the enzyme PDE5, preventing the breakdown of cyclic guanosine monophosphate (cGMP).
• Increased levels of cGMP result from nitric oxide (NO) release during sexual stimulation.
• This leads to smooth muscle relaxation in blood vessels, enhancing blood flow to the penis and facilitating an erection.

Indicazioni

• Tadalafil is primarily indicated for treating erectile dysfunction in men.
• It also addresses benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension under the brand Adcirca.

Inizio dell'azione

• The onset usually occurs within 30 minutes to 1 hour post-administration.

Durata dell'azione

• Tadalafil can provide effects lasting up to 36 hours, earning it the nickname “weekend pill.”
• This duration allows men to maintain an erection during that time upon sexual stimulation.

Dosaggio

• Typical doses for erectile dysfunction range from 10 mg to 20 mg, taken about 30 minutes before anticipated sexual activity.
• For treating BPH, a daily dose of 5 mg is recommended.

Effetti collaterali

• Common side effects of Tadalafil may include headache, facial flushing, indigestion, dizziness, muscle discomfort, and back pain.
• In rare cases, severe side effects like sudden vision or hearing loss may occur.

Controindicazioni

• Avoid Tadalafil with nitrates (e.g., nitroglycerin) due to the risk of significant blood pressure drops.
• It is contraindicated in individuals with severe cardiovascular issues, recent heart attacks, or strokes.